DHM (Dihydromyricetin) is a flavonoid compound found in plants such as Hovenia Dulcis, also known as the Oriental Raisin Tree. It has been traditionally used in Chinese medicine to alleviate hangover symptoms.

DHM has two key benefits. First, it has been clinically shown to help reduce the severity of hangover symptoms. By accelerating the activity of enzymes (ADH and ALDH), DHM increases the breakdown of ethanol to acetaldehyde and subsequently to acetate, which the body can eliminate easily. This reduces the level of acetaldehyde in the body - the cause of many hangover symptoms, alleviating the effects of hangovers.

The second beneficial aspect of DHM is the presence of Semen Hoveniae, which possesses anti-inflammatory and antioxidative properties. This attribute can aid in reducing the activities of alanine aminotransferase (ALT) and aspartate transaminase (AST), two enzymes associated with liver damage caused by alcohol consumption. As a result, DHM is beneficial in safeguarding the liver against acute alcohol-induced injury.

Curcumin is a natural compound found in turmeric, a spice commonly used in Indian and Southeast Asian cuisine. It is known for its anti-inflammatory and antioxidant properties, and has been used in traditional medicine for centuries to treat various ailments.

Its antioxidant and anti-inflammatory properties increase the activities of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) in response to alcohol to reduce acetaldehyde. Additionally, curcumin increases the activities of antioxidant enzymes such as glutathione peroxidase in liver tissues, which prevents injury and inflammation of the liver.

Ginger root extract has been traditionally used for its medicinal properties. It is known for its anti-inflammatory, antioxidant, digestive, and anti-nausea properties, among others.

Its anti-inflammatory and antioxidant properties help alleviate symptoms commonly associated with hangovers, such as nausea, vomiting, and digestive discomfort. Additionally, it can protect the liver against alcohol-induced damage by reducing oxidative stress, inflammation, and liver enzyme levels.

Black pepper fruit extract, derived from the dried fruit of the Piper nigrum plant, is often used in supplements and herbal remedies due to its therapeutic properties.

Black pepper fruit extract contains a compound called piperine, which helps improve the bioavailability and effectiveness of other components such as Curcumin, allowing for better absorption. Its hepatoprotective properties also help protect the liver from damage caused by alcohol consumption.